How Uribel Works

Uribel treats more than just pain

Uribel is a prescription medicine used to relieve the discomfort, pain, frequent urge to urinate, and cramps/spasms of the urinary tract caused by a urinary tract infection or a diagnostic procedure. Some urinary medicines contain only 1 ingredient—an analgesic for pain relief. Uribel contains 5 ingredients that work together to treat your symptoms:

A pain reliever to treat pain and burning sensations when you urinate
An antispasmodic to help relax the smooth muscle tissue of your urinary tract
A combination of antiseptic ingredients^*

What to expect when taking Uribel

Adult Dosing: Take one Uribel capsule 4 times a day; however, please follow your doctor’s instructions
Older Children Dosing: Follow your doctor’s individualized dosing (Not recommended for use in children 6 and under)
Take each Uribel dose with ample amounts of fluid
Uribel may be used in conjunction with antibiotic therapies or other medicines^1,2; however, ask your doctor to be sure there are no potential drug interactions
You should not take more than the recommended dose of Uribel capsules
Uribel typically causes your urine to turn blue or bluish-green and may also affect the color of your stool. This is a harmless effect

^*Uribel does not replace antibiotic therapy prescribed by your doctor.

Each dose is one capsule that should be taken with plenty of fluid.

References

McPhee JS, Papadakis MA, eds. Current Medical Diagnosis and Treatment. New York, NY: McGraw-Hill Medical; 2009: 828-838.
Panzera AK. Interstitial cystitis/painful bladder syndrome. Urol Nurs. 2007 Feb:27(1):13-19.

Important Safety Information

Uribel is not for everyone. You should not take Uribel if you are allergic to hyoscyamine, methenamine, methylene blue, or phenyl salicylate. Tell your doctor immediately if you develop any of the following symptoms: itching, rash, severe dizziness, swelling, or trouble breathing. These could be signs of a serious allergic reaction.

You should not take more than the prescribed dose of Uribel. If you experience a rapid pulse, dizziness, or blurred vision, discontinue use immediately. The effects of long-term use of Uribel are not known.

Tell your doctor about all your medical conditions and all medicines that you take. To make sure this medicine is safe for you, tell your doctor if you have:

heart disease, including a heart rhythm disorder, congestive heart failure, coronary heart disease or a heart valve disorder;

glaucoma;

an enlarged prostate or bladder obstruction;

myasthenia gravis;

an ulcer or obstruction in your stomach or intestines;

an allergy or hypersensitivity to belladonna or salicylates like NSAIDs and aspirin.

It is not known whether this medication will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Some of the ingredients in Uribel can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast feeding a baby.

This medicine should not be given to young children or infants. Elderly adults may be more likely to have side effects such as excitement, agitation, drowsiness or confusion from this medication.

This medication may interact with other drug products. Keep a list of all the medicines you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Before taking Uribel, tell your doctor about all medications you are taking including digoxin, warfarin, phenytoin, alfenatil, cyclosporine, dihydroergotamine, ergotamine, fentanyl, pimozide, quinidine, sirolimus, and tacrolimus.

It is also important that your doctor know if you are taking products that decrease the amount of acid in the urine (such as antacids, sodium bicarbonate, potassium/sodium citrate, acetazolamide), diuretics (water pills), medicines used to treat asthma and COPD, and medicines used to treat certain gastrointestinal and urinary tract disorders (e.g., overactive bladder), and drugs to treat diarrhea. If you are taking any of these medications and your doctor prescribes Uribel, you should take this product at least one hour before or after taking these other medications. You should also tell your doctor if you are taking medications for myasthenia gravis, sulfonamide drugs (including sulfa antibiotics such as sulfamethoxazole), narcotic pain medications, MAO inhibitors, or antifungal medicines. If you are taking certain antifungal drugs (such as ketoconazole), take this product at least 2 hours after the antifungal drug. Taking MAO inhibitors (isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine) with this medication may cause a serious drug interaction. Ask your doctor when to start or stop taking these medications. Do not start any new medications, or stop or change the dosage of any medications you are taking without your doctor's approval.

The most common side effects of Uribel are rapid heartbeat, flushing, blurred vision, dizziness, drowsiness, difficulty urinating, inability to urinate, dry mouth, nausea, vomiting, shortness of breath or trouble breathing. This medicine can cause your urine and sometimes your stools to turn a bluish color. This effect is harmless and will stop after the medication is discontinued.

Seek immediate medical attention if you notice symptoms of a serious allergic reaction such as itching, rash, severe dizziness, swelling, or trouble breathing.

Call your doctor for medical advice about side effects. You may report negative side effects to Mission Pharmacal Company at 1-800-298-1087, or to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.